Purpose: A pilot randomised controlled trial (RCT) to examine the feasibility and efficacy of a supervised, multicomponent exercise program in patients with localised pancreatic cancer undergoing preoperative therapy.
Inclusion Criteria:
- Age ≥18 years.
- Waiting to start or within 8 weeks of induction chemotherapy .
- Approved by their treating oncologist to participate in the trial.
Exclusion criteria:
- Recurrent pancreatic cancer with or without exposure to previous chemotherapy.
- Having undergone treatments for another primary cancer within the last 12 months, or another ongoing active primary malignancy.
- Anticipating undergoing major surgery for non-cancer diseases within the next 6 months.
- Any musculoskeletal, cardiovascular or neurological disorder that could put patients at risk during exercise testing and training.
- Having participated in planned, individualised and supervised exercise training for ≥2 days/week in the previous month.