Established in 2003, the Exercise Medicine Research Institute houses an innovative, multidisciplinary and productive research team in exercise science dedicated to investigating the extent to which exercise can be employed in chronic disease management, principally cancer, to materially improve patient outcomes. The team’s unique convergence of clinical patient care, exercise medicine, and innovation in health interventions has underpinned their achievements in cancer research. Most notably, their multifaceted research program has been the direct result of seminal work in prostate cancer enabling direct translation of their research findings into practical outcomes for patient benefit and the design and implementation of clinical and community based cancer survivorship programs.